If you have a W210 that has the 722.6 already installed.

First this controller is not made for cars that has the 722.6 already in.

But if you are tuning the engine and so on, using aftermarked Engine controller, yes then it make sence to use this gearbox controller

If it is an OM606 with 722.6 Gearbox. (E300 Turbodiesel)

If you change Electric injection pump with OM603 pump, then the engine will run

There can be a problem if the Gearlever plug is removed from gear Lever that the car will not start. but

that can be handlet by leaving the originally plug in and not connect "OF Gear" Gearlever plug.

If it is an gasoline engine i6 or V8

If you change engine controller to aftermarked, you should be good but still.

There can be a problem if the Gearlever plug is removed from gear Lever that the car will not start. but

that can be handlet by leaving the originally plug in and NOT connect "OF Gear" Gearlever plug.

If you want to use the originally engine controller.

Then try to remove big gearbox plug from gearbox

Start engine, put in D now you are in 2 gear and it will stay there.

Drive and test if engine has full power or in Limp home mode.

If no Limp mode try to remove gear Lever plug and see if engine can start ?

If it does not start put back the gear Lever plug, and just not connect "OF Gear" Gear Lever plug

Before you order

1. Make sure you engine does not goes in to limp mode, if big gearbox plug is removed.

2. Accept that you do not have the originally function in the gearlever. hold in gear and W/S switch

3. Accept that all other function in the car is working is you own responsibility.

When does it make sense to order this controller for W210 Car

1. If you have tuned it heavely and the transmission goes in to fail mode

2. If you have mounted aftermarked engine controller and the car does not shift gear.

3. You want to have paddle shifters, and instand shift.

4. Have the possibility to adjust when it should shift.

To cheat the car to start you can try this, if originally TCU Gearlever plug is removed from gearlever.

You do this to the CAR originally TCU gearlever plug. not to the gearlever.

I have not tryed it myself as i do not have a W210  

PLESE IT IS ON YOU OWN RISK. (But has been confirmed to work on R170, W202, W208 and W210

)

BUT LET ME KNOW IF IT WORKS.

Connect

Pin 10 to Pin 3 (GND)  (maby use an 1K resistor to be sure not to harm anything)

Connect

Pin 4 to Pin 1 (5V) (maby use an 1K resistor to be sure not to harm anything)

Pin 5 to Pin 1 (5V) (maby use an 1K resistor to be sure not to harm anything)

Pin 9 to Pin 1 (5V) (maby use an 1K resistor to be sure not to harm anything)

Or an other way to get it to start 

Is that you can buy an old used Gear Lever take it apart, and only use the electronic inside to connect to the W210 Harness and make sure the electronic module is in N, That way car is happy and will start. 

Then connect this controller to original gearlever